Renal protective effect of dexmeditomidine in patients undergoing abdominal aortic surgeries

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

PACTR

Registry ID

PACTR202402909858685

Enrollment

Registered

2024-02-15

Start date

2024-02-15

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

dexmedetomidine

control

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: American Society of Anaesthesia (ASA) physical status class II – III Age from 40-65 years Elective aortobifemoral bypass surgery utilizing a synthetic graft under general anaesthesia.

Exclusion criteria

Exclusion criteria: severe renal impairment (chronic kidney disease stage III or IV) renal artery stenosis or atherosclerosis previous renal surgery, single kidney suprarenal cross clamping severe hepatic insufficiency and emergency surgery.

Design outcomes

Primary

Measure	Time frame
The primary outcome is to measure the urinary Kidney injury molecule -1 as a predictor of acute kidney injury following aortic cross clamping in abdominal aortic aneurysm	—

Secondary

Measure	Time frame
- Serum creatinine. - Urea and blood urea nitrogen - Creatinine clearance. ;Haemodynamic parameters: - Heart rate (beats/min). - Invasive mean arterial blood pressure (mmHg). ;Postoperative need for renal dialysis.	—

Countries

Egypt

Contacts

Public ContactMohamed Abdelaal

Professor of cardiothoracic surgery Kafrelsheikh university Egypt

malaal2@hotmail.com+201001422577

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026