Rotational Thromboelastometry Guided Transfusion Protocol versus Classical Transfusion Protocol in Reducing Blood Components Transfusion in Adult Patients Undergoing Elective Cardiac Surgery

Rotational Thromboelastometry Guided Transfusion Protocol versus Classical Transfusion Protocol in Reducing Blood Components Transfusion in Adult Patients Undergoing Elective Cardiac Surgery: A Randomized Clinical Trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

PACTR

Registry ID

PACTR202402769956111

Enrollment

Registered

2024-02-06

Start date

2019-10-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

Classical transfusion protocol

ROTEM guided transfusion protocol

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - Patients undergoing elective primary cardiac surgery on cardiopulmonary bypass (coronary artery bypass graft, valve replacement or coronary artery bypass graft with valve replacement) - ASA II or III - More than 18 years-old (both sexes)

Exclusion criteria

Exclusion criteria: - Emergent cardiac surgeries. - Re-do cardiac surgeries. - Patients taking oral anticoagulants within 5 days of surgery or low molecular weight heparin until the day of surgery. - Patients with congenital or acquired coagulopathy. - Patients with impaired liver functions (elevated liver enzymes) - Patients with impaired renal functions (serum creatinine > 2 mg/dL) - Patients with body mass index 35 kg/m2

Design outcomes

Primary

Measure	Time frame
Post-bypass blood components transfusion requirements.;Postoperative blood components transfusion requirements	—

Secondary

Measure	Time frame
Postoperative blood loss measured as chest tube drainage after exclusion of surgical cause of bleeding;Detecting residual heparin after its reversal with protamine	—

Countries

Egypt

Contacts

Public ContactAhmed Mahdy

Lecturer of Anesthesia and Intensive Care Faculty of Medicine Suez Canal University

ahmed.mahdy@med.suez.edu.eg+201025572557

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026