Anaesthesia
Conditions
Interventions
Sponsors
natioanl liver institute
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Adult patients who will have elective surgical operations under general anesthesia. (2) Age: Patients age 18–65 years, of both sexes. (3) American Society of Anesthesiologists (ASA) grade I–II (4) Body mass index (BMI) 18.5–35 kg/m2. (5) Airway of Modified Mallampati Grade I and II
Exclusion criteria
Exclusion criteria: (1) Patient refusal to participate in the study. (2) Morbid obesity Body mass index higher than 35 kg/m2 (3) Patients with pacemakers and cardiac arrhythmia. (4) Uncontrolled diabetes mellitus, hypertension, ischemic heart disease, , history of myocardial, pulmonary, or endocrine diseases, , hepatic or renal impairment. (5) Pregnancy, full stomach, emergency surgery. (6) Patients who are allergic to any of the study drugs, those with opioid addiction. (7) Patients on beta blocker or calcium channel blocker. (8) Patients who had Cormack Lahane score III and above and also those in which the duration of laryngoscopy lasted more than 25 seconds.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| compare changes in analgesia nociception index [ANI] during direct laryngoscopy and endotracheal intubation in patients undergoing elective surgeries after premedication by dexmedetomidine in two different doses | — |
Secondary
| Measure | Time frame |
|---|---|
| to find out the optimum dose of dexmedetomidine given as premedication according to changes in the ANI correlated to hemodynamics | — |
Countries
Egypt
Contacts
Public Contacthanaa rashed
lecturer of anasthesia
Outcome results
None listed