Cancer
Conditions
Interventions
Magnesium replacement therapy
Regular post total thyroidectomy treatment
Sponsors
Dr Ahmed Serag
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: • Patients suffering from hypocalcaemia post total thyroidectomy at National Cancer Institute. • At least one parathyroid gland must be preserved with normal PTH levels. • Adults only will be included (age from 18 to 65 years). • Preoperative serum calcium, magnesium, phosphorus and vitamin D levels are normal in all patients.
Exclusion criteria
Exclusion criteria: • Infants and children (age 65 years) • Pregnant women • Cognitively impaired or mentally disabled subjects • Patients with history of thyroid surgeries • All parathyroid glands are lost during surgery • Severe symptomatic hypocalcaemia needing to be treated with intravenous calcium for emergency expressed as seizures or tetanic convulsions including Trousseau`s sign and Chvostek`s sign (with cut-off point of calcium level 50 IU/L , Aspartate aminotransaminase (AST) > 40 IU/L and Total bilirubin > 1.2 mg/dl ) • Patients taking any medication that would affect calcium levels such as, Thiazide diuretics, lithium, rifampicin, phenytoin, Bisphosphonates, Dietary supplements containing calcium and vitamins affecting calcium level such as vitamin D, etc. • patients with other types of cancer other than thyroid cancer (e.g. any metastasis).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The effect of magnesium replacement therapy on hypocalcaemia post total thyroidectomy. | — |
Secondary
| Measure | Time frame |
|---|---|
| The prevalence of symptomatic hypocalcaemia post total thyroidectomy. | — |
Countries
Egypt
Contacts
Public ContactAbd El Wahab Raafat
Department of Surgical Oncology at National Cancer Institute Cairo University
Outcome results
None listed