Nutritional, Metabolic, Endocrine Fertility-female
Conditions
Interventions
Folic acid
Celine TM
Sponsors
Jehan Elfarjani
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: - Women aged 20-40 years at the time of enrollment - diagnosed with PCOS (according to the Rotterdam criteria, represented by oligomenorrhea, hyperandrogenism or hyperandrogenemia, and typical ovarian features on ultrasound), - and undergoing in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) treatment. - Normal uterine cavity as assessed by hysteroscopy or hysterosalpingography and normal prolactin and thyroid-stimulating hormone levels were required.
Exclusion criteria
Exclusion criteria: Women with male factor infertility, such as azoospermia Women with other medical conditions causing ovulatory dysfunction, such as hyperprolactinemia, hypothyroidism, or adrenal hyperplasia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measures were oocyte parameters, including preovulatory follicle count, which reflects the number of preovulatory follicles >17mm in size, total number of oocytes retrieved, which typically ranges from 6 to 15; oocyte quality, defined by the number of MII oocytes retrieved; and the number and quality of embryos transferred, based on the number of morphologically Grade 1 embryos. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes included duration of ovarian stimulation, number of gonadotropin vials used reflecting total gonadotropin dose, and pregnancy based on ultrasound. | — |
Countries
Libyan Arab Jamahiriya
Contacts
Public ContactPatrick Choueiry
Global Medical Director at Surveal
Outcome results
None listed