Circulatory System Mental and Behavioural Disorders
Conditions
Interventions
Bilateral digital carotid compression
Non compression of the carotid arteries
Sponsors
Cairo University Hospitals
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients scheduled for mitral valve replacement surgery Patients aged 18-60 years
Exclusion criteria
Exclusion criteria: Disturbed Conscious Level (Glasgow Coma Scale less than 15) Substance abuse MMSE score less than 24 points Emergency cases Patients unable to read and write Previous strokes or transient ischemic attacks Significant carotid artery stenosis more than 50 % Previous serious psychiatric or neurologic disorders Previous atrial fibrillation within the last 6 months Renal impairment, liver disease, or severe chronic obstructive pulmonary disease A drop in mean arterial blood pressure by more than 20% before bypass and a mean arterial blood pressure less than 60 mmHg during bypass End tidal CO2 less than 35 mmHg or more than 40 mmHg Partial pressure of oxygen less than 150 mmHg or more than 250 mmHg
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Short-term POCD | — |
Secondary
| Measure | Time frame |
|---|---|
| Short-term POCD ;Correlation of occurrence of short-term POCD with transcranial Doppler | — |
Countries
Egypt
Contacts
Public ContactReham Kaddah
Department of Anesthesia Surgical Intensive Care and Pain Management Faculty of Medicine Cairo University
Outcome results
None listed