Pregnancy and Childbirth
Conditions
Interventions
Tranexamic acid
Ethamsylate
Sponsors
Adebayo Saheed Y.
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: i. Women within the ages of 18 to 35year ii. No contraindication for spinal anaesthesia iii. American Society of Anesthesiologists’ physical status 1 and 11 iv. Women who give written informed consent
Exclusion criteria
Exclusion criteria: History of bleeding disorder, arterial or venous thrombosis ii. Co-existing medical conditions e.g. renal, liver disease iii. Multiple gestation iv. Polyhydramnios v. Co-existing uterine fibroid vi. Abnormal placentation vii. History of allergy to tranexamic acid or ethamsylate viii. Use of low dose aspirin or any anticoagulant ix. Body mass index at booking 30kg/m2
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Intraoperative and postoperative blood loss using visual and gravimetric assessment. 2. Preoperative and postoperative haemoglobin level using Brecher et al method. 3. Proportion of postpartum haemorrhage 4. Need for blood transfusion | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Patients with any untoward side effect especially unilateral leg swelling, difficulty in breathing. 2. Patient’s satisfaction with intervention using Likert’s scale | — |
Countries
Nigeria
Contacts
Public ContactSaheed Adebayo
Senior registrar
Outcome results
None listed