Uterine fibroid
Conditions
Interventions
Tranexamic acid and Tourniquet group
Tourniquet and Placebo alone group
Sponsors
DR. AMULU IFEANYI VICTOR
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Women in reproductive age with symptomatic uterine fibroid, booked for open abdominal myomectomy at the study centers were recruited for this study.
Exclusion criteria
Exclusion criteria: Women with the following history and co-morbid conditions were excluded from the study. 1. Patients with history of myomectomy in the past, 2. Use of GnRH analog before surgery 3. Allergy to the use of tranexamic acid 4. Thromboembolic disorders 5. Renal impairment 6. Obese (weight >30kg/m2)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean estimated volume of intra-operative blood loss in milliliter in the study and control groups | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Mean estimated volume of total blood loss in milliliter in both study group and control group. 2. Mean difference between pre-operative and post-operative haemoglobin in g/dl for study and control groups 3. The average number of pints of blood transfused per participant in both groups. | — |
Countries
Nigeria
Contacts
Public ContactGeorge Eleje
Consultant Obstetrician and Gynaecologist Department of OBGYN Nnamdi Azikiwe University Teaching Hospital Nnewi Nigeria
Outcome results
None listed