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Effect of single versus double layer uterine closure during caesarean section on niche formation and menstrual irregularity

Effect of single versus double layer uterine closure during caesarean section on niche formation and menstrual irregularity: A randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202312583411798
Enrollment
297
Registered
2023-12-13
Start date
2022-10-25
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy and Childbirth

Interventions

Double layer continuous uterotomy suture
Single layer continuous uterotomy suture

Sponsors

Ahmed Mohamed
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1) Primigravida women undergoing elective cesarean section, 2) Singleton term pregnancies after 37 gestational weeks, 3) Age: 18 – 40 years, 4) Non lactating and non-hormonal contraception.

Exclusion criteria

Exclusion criteria: a) Previous uterine surgery (myomectomy or metroplasty), b) Women with known causes of menstrual disorders (abnormal Uterine Bleeding in the form of premenstrual or postmenstrual spotting, dysmenorrhea, and amenorrhea), c) Placenta accreta spectrum during the current pregnancy, d) Cases associated with poor wound healing as steroid administration or patients with antenatal anemia, e) Medical conditions as diabetes mellitus, f) Risk of endometritis and puerperal sepsis g) Postpartum hemorrhage.

Design outcomes

Primary

MeasureTime frame
Post-menstrual spotting over 3 successive spontaneous menstrual cycles.

Secondary

MeasureTime frame
Ultrasound findings suggestive of niche formation;Dysmennorhea, dyspareunia, and premenstrual spotting.

Countries

Egypt

Contacts

Public ContactAhmed Mohamed

Assistant professor Obstetrics and Gynecology

ma0974846@gmail.com+201151366151

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026