Skip to content

Postoperative pain control and quality of life following the use of preemptive celecoxib in mandibular third molar surgery

Postoperative pain control and quality of life following the use of preemptive celecoxib in mandibular third molar surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202311897703701
Enrollment
62
Registered
2023-11-16
Start date
2023-09-26
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Health

Interventions

Preemptive analgesia

Sponsors

Stephen Solomon
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients within the age ranges of 18 to 50 years. 2. Patients who shall be willing to keep instructions and follow-up appointments. 3. Patients with mandibular third molar impaction requiring surgical extraction 4. Patients who give their consent to be part of the study 5. American Society of Anaesthesiologist physical status classification I (ASA I) patients

Exclusion criteria

Exclusion criteria: 1. Patients with a history of allergy to celecoxib. 2. Patients who are allergic to penicillins and metronidazole 3. Patients who used NSAIDs or any other analgesic within 24 hours before the procedure 4. Patients with a bleeding disorder or on anticoagulant 5. Patients with peptic ulcer disease, kidney disease, asthma or any medical condition that contradict the use of NSAIDs. 6. Pregnant women 7. Patients with periapical cysts or tumours related to the impacted third molar 8. Patients that could not be able to rate their pain intensity on the VAS due to medical conditions such as problems with vision, mental retardation, cognitive disorder, or any other reason. 9. Patients who smoke, take alcohol or abuse drugs (illicit drugs)

Design outcomes

Primary

MeasureTime frame
Pain intensity to measured by the participants following the procedure using the Visual Analogue Scale VAS ;Health related quality of life

Secondary

MeasureTime frame
Rescue analgesic demand recorded by the number of times the rescue analgesia was required/taken by the participants within the first 24 hours

Countries

Nigeria

Contacts

Public ContactAkinwale Efunkoya

Professor Oral and Maxillofacial surgeon Aminu Kano Teaching Hospital

akinefunks12@gmail.com+2348065454401

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026