Circulatory System Orthopaedics Anaesthesia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1- Patients of both sexes aged 18 to 70 undergoing lower limb orthopedic surgery using spinal anesthesia. 2- Height from 160 cm to 180 cm. 3- American Society of Anesthesiologist physical status I, II or III.
Exclusion criteria
Exclusion criteria: 1. Patients who refuse to participate in the study 2. Elevated BP (>160/100 mm Hg) 3. Failed spinal anesthesia 4. Patients with known cardiovascular disease 5. Patients with known cerebrovascular disease 6. Patients with known neurological, neurodegenerative or psychiatric disease 7. Patients with known liver failure 8. Clinical history of diabetes 9. Contraindication to spinal anaesthesia e.g. coagulopathy, H 10. Patients with known caffeine or coffee allergy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| to investigate the efficacy of prophylactic preoperative caffeine in preventing spinal anesthesia-induced hypotension | — |
Secondary
| Measure | Time frame |
|---|---|
| the total amounts of rescue ephedrine and atropine and the incidences of nausea/vomiting requiring treatment between the groups. The incidence of post dural puncture headache and postoperative delirium will be recorded. | — |
Countries
Egypt
Contacts
Resident of anesthesia Mansoura University Hospital