Anaesthesia
Conditions
Interventions
groups receiving either haloperidol or dexmedetomidine combined with ondansetron
group receiving only ondansetron without adjuvants
Sponsors
Faculty Of Medicine Ain Shams University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age (18 – 65) undergoing laparoscopic cholecystectomy. 2. American Society of Anesthesiologist (ASA)- physical status I & II 3. No history of psychiatric illness 4. No Parkinson's disease, motion sickness or history of chemotherapy 5. Both gender
Exclusion criteria
Exclusion criteria: 1. Patients on (steroids, antiemetics, or any drug that may cause emesis). 2. Pregnancy. 3. Any active cardiac or chest condition at the time of surgery 4. ASA = III and IV physical status 5. Parkinson's disease 6. Patients with psychiatric disease history 7. Patients on chemotherapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| •Incidence of PONV in the 1st postoperative 24 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| • The number of nausea and vomiting attacks. • Severity of postoperative nausea and vomiting using a 10 cmVAS score rating scale. • Use of rescue aniemetic • Assessment of postoperative pain using VAS score • The sedation scores (Observer’s Assessment of Alertness/Sedation (OAA/S) scale) (where 1 =awake/alert, 2=light sedation, 3=moderate sedation, 4=deep sedation and 5 = deep sleep) | — |
Countries
Egypt
Contacts
Public ContactMostafa Abu Sekkien
Assistant Lecturer in Department of Anesthesia and Icu Ain shams University
Outcome results
None listed