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Effect of an exercise intervention on fitness, perceptual-cognitive functioning and selected biomarkers of depression in persons with Major Depression

Effect of an exercise intervention on fitness, perceptual-cognitive functioning and selected biomarkers of depression in persons with Major Depression

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202311572866804
Enrollment
100
Registered
2023-11-23
Start date
2024-01-15
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mental and Behavioural Disorders

Interventions

Stretching to mask exercise

Sponsors

North West University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: • Persons diagnosed with a mild to moderate Major Depression according to the BDI-scale (score between 10 – 29); • Diagnosed with depression for the first time; • Between the ages of 18-25 years; • Not using antidepressant medication; and • Not engaging in psychotherapy sessions at a preferred practitioner.

Exclusion criteria

Exclusion criteria: • use antidepressant medication; • absolute contraindications for exercise participation according to ACSM guidelines; • participants with orthopaedic limitations; • pregnant or lactating women; • participants who diagnosed with post-natal depression; • participants with bipolar depression; and • participants diagnosed with severe Major Depression.

Design outcomes

Primary

MeasureTime frame
Beck Depressive Index score ;Perceptual-cognitive function with Multi-object tracking;Cardiorespiratory fitness;Cortisol concentrations;Habitual physical activity

Secondary

MeasureTime frame
Body composition;Screen time;Association between Beck Depression Index and cortisol concentrations

Countries

South Africa

Contacts

Public ContactWayne Towers

Head of Ethics Health sciences

Wayne.towers@nwu.ac.za+27182992092

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026