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Effects of metformin phonophoresis and exercise therapy on knee pain, range of motion, and function in knee osteoarthritis

Effects of metformin phonophoresis and exercise therapy on knee pain, range of motion, and function in knee osteoarthritis

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
PACTR
Registry ID
PACTR202311507335269
Enrollment
85
Registered
2023-11-09
Start date
2022-11-10
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Musculoskeletal Diseases

Interventions

Metformin phonophoresis US
metformin phonophoresis added to conventional exercise program
US with neutral non drug gel

Sponsors

Cairo university
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. unilateral moderate knee OA based on the American College of Rheumatology criteria (ACR) 2. Age of the subjects was between 40-60 years . 3. Body mass index (BMI) was 18.5-29.9 kg/m2.

Exclusion criteria

Exclusion criteria: 1. Rheumatoid arthritis 2. Severe knee OA 3. Thrombosis of the lower limbs 4. Previous surgery on the knee joint 5. Previous fracture of the lower extremity with knee joint involvement 6. Any contraindications or precautions for the use of ultrasound (e.g., infection, heart problems, pacemaker, metal implants, open epiphysis, pregnancy 7. Thrombophlebitis

Design outcomes

Primary

MeasureTime frame
knee pain , knee function

Secondary

MeasureTime frame
knee flexion and extension ROM;physical performance

Countries

Iraq

Contacts

Public ContactElsadat Soliman

Assistant Professor of Physical Therapy Department for Musculoskeletal System Disorders and their Surgeries Faculty of Physical Therapy Cairo University

sadatsaad@yahoo.com+2011128911820

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026