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Effects of exercise therapy on cardiovascular disease (CVD) risk among people living with Human Immunodeficiency Virus in Ndirande, Malawi: A step towards designing a sustainable CVD prevention strategy

Effects of exercise therapy on cardiovascular disease (CVD) risk among people living with Human Immunodeficiency Virus in Ndirande, Malawi: A step towards designing a sustainable CVD prevention strategy

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
PACTR
Registry ID
PACTR202310853413416
Enrollment
40
Registered
2023-10-12
Start date
2023-10-16
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Circulatory System HIV/AIDS Nutritional, Metabolic, Endocrine Cardiology

Interventions

Exercise therapy
individualized education and counselling targeting healthy behaviour change

Sponsors

Alice Namanja
Lead Sponsor
Professor Sean Carroll
Collaborator
Dr. James Hobkirk
Collaborator
Professor Johnstone Kumwenda
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Are aged between 25 and 45 years 2. Are within the first (highest risk) tertile of participants with relatively higher values of 30-year CVD risk scores 3. Have a reliable mobile phone in their household, which they can use to receive personalized messages and phone calls in this study 4. Are from within and immediate surrounding areas of Ndirande township

Exclusion criteria

Exclusion criteria: 1. Have any physical, visual, and hearing impairments that may limit their level of participation in physical exercise 2. Are pregnant or breastfeeding 3. Have any diagnosed opportunistic infection or are sick

Design outcomes

Primary

MeasureTime frame
Peak oxygen consumption;30-year Cardiovascular disease risk score;cardiovascular health status score;Quality of life

Secondary

MeasureTime frame
Biomarkers of inflammation and cardiac dysfunction, including NTproBNP, C-RP, HbA1C and fasting glucose;Visceral Adiposity index score

Countries

Malawi

Contacts

Public ContactAlice Namanja

Lecturer at Kamuzu University of Health Sciences Malawi PhD student at the University of Hull England United Kingdom

anamanja@kuhes.ac.mw+265997759408

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026