Use of Sildenafil Citrate in the Management of Unexplained Infertility in Kisangani, Democratic Republic of Congo

Clomiphene citrate and Sildenafil citrate versus Clomiphene citrate and Estradiol valerate for Induction of ovulation in congolese patient with unexpalined infertility: A Randomised Controlled Trial.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

PACTR

Registry ID

PACTR202310849449401

Enrollment

144

Registered

2023-10-12

Start date

2021-07-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fertility-female

Interventions

Sildenafil citrate

Estradiol valerate

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Women aged 19-34, whose infertility tests were normal then diagnosed as unexplained infertility. Informed (written) consent to participate in the study.

Exclusion criteria

Exclusion criteria: Any cause of infertility (male factors, tubal or ovarian factors, or any other factors) Chronic illness as cardiac or renal disease Any contraindication for used drugs Refusal to participate in the study.

Design outcomes

Primary

Measure	Time frame
Conception rate (clinical pregnancy)	—

Secondary

Measure	Time frame
Thickness and echogenicity of the endometrium Velocity of uterine blood flow (pulsatility index and resistance index) Number of mature follicles Ovulation rate	—

Countries

Democratic Republic of the Congo

Contacts

Public ContactLabama Otuli

Faculty of Medicine and Pharmacy

nlabama@gmail.com+243813229686

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026