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The effect of two varying doses of intravenous tranexamic acid on blood loss after vaginal delivery at term in University of Benin Teaching Hospital

The effect of two varying doses of intravenous tranexamic acid on blood loss after vaginal delivery at term in University of Benin Teaching Hospital: a double-blinded randomized placebo controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202310814099421
Enrollment
135
Registered
2023-10-10
Start date
2024-01-01
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

primary postpartum haemorrhage

Interventions

sterile water
tranexamic acid

Sponsors

Centre for excellence in reproductive health initiative
Collaborator

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: All women with gestation age between 37 completed weeks to 41weeks and 6days and Parity 0-4 admitted in labour (spontaneous labour or induction of labour) Gave consent for the study Had vaginal delivery

Exclusion criteria

Exclusion criteria: Any woman with gestation age between 37 completed weeks to 41weeks and 6days admitted in labour (spontaneous labour or induction of labour) who did not give consent for the study Any woman who has history of thrombosis or epilepsy, history of medical/surgical conditions involving the heart, liver, kidney and brain, have known allergy to tranexamic acid, and bleeding disorders and abnormalities before pregnancy. Eventually delivered by Caesarean section after meeting inclusion criteria

Design outcomes

Primary

MeasureTime frame
mean blood loss

Secondary

MeasureTime frame
change in haematocrit and haemoglobin concentration from before and after delivery;need for additional uterotonic;need for blood transfusion

Countries

Nigeria

Contacts

Public ContactMichael Orhue

Specialist Registrar

mykelorhue@gmail.com+2348039473079

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026