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Comparative evaluation of efficacy of biodentine, mineral trioxide aggregate, calcium hydroxide and glass ionomer cement as pulp capping agent in deep carious lesions

Comparative evaluation of efficacy of biodentine, mineral trioxide aggregate, calcium hydroxide and glass ionomer cement as pulp capping agent in deep carious lesions

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202310667867616
Enrollment
205
Registered
2023-10-26
Start date
2023-07-10
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Health

Interventions

Indirect pulp capping with calcium hydroxide
Indirect pulp capping using MTA
Indirect pulp capping with GIC

Sponsors

Adamu Abdullahi Biu
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. All consenting adult subjects above 18 years of age, in good general health, presenting at the oral diagnosis and restorative dentistry clinics of UMTH. 2. Adults with at least one permanent molar are diagnosed to have an active DCL with or without irreversible pulpal damage or periapical involvement. 3. Any occlusal (G.V black class I) DCLs of at least 2/3rd depth or more into dentin thickness.

Exclusion criteria

Exclusion criteria: 1. Subjects with DCLs with signs and symptoms of irreversible pulp inflammation or periapical inflammation. These include tooth/teeth with: a. Previous restorations b. History of related swelling c. Tenderness to palpation and/or percussion d. Grossly broken-down tooth e. Advanced periodontal diseases: grade III mobility f. The true negative response to pulp sensibility test g. Coronal radiolucency due to caries that is less than 2/3rd of the dentine thickness. h. Pulpal bleeding (exposure) during caries excavation i. Third molars. 2. Subjects with para-functional habits. 3. Subjects that have been on antibiotics or steroids six weeks prior to the study period. 4. Pregnant women.

Design outcomes

Primary

MeasureTime frame
pain

Secondary

MeasureTime frame
radiographic thickness of residual dentine and new dentine formation

Countries

Nigeria

Contacts

Public ContactPAUL IDON

consultant restorative dentistry

idonp53@gmail.com+2348033890578

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026