Pregnancy and Childbirth Surgery
Conditions
Interventions
Combined misoprostol and oxytocin
Oxytocin plus placebo
Sponsors
Federal Government of Nigeria
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Consenting women with term pregnancies undergoing elective lower segment caesarean delivery under spinal anaesthesia.
Exclusion criteria
Exclusion criteria: Women with predisposing factors for PPH, such as; Multiple gestations, Placenta praevia, Undiagnosed vaginal bleeding, were excluded from the study. Patients who had general anaesthesia Patients with surgical indications requiring general anaesthesia, cardiovascular, renal, or hepatic dysfunction. Patients who presented with fever or refused to give consent were excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measure was blood loss (intra-operative and postpartum within 24 hours of delivery) estimated in millilitres. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcome measures included; a significant change in pre- and post-delivery haematocrit, the need for additional uterotonic interventions in the 24 hours following delivery to maintain proper uterine tone, the need for blood transfusion, and medication side effects such as fever, headache, shivering, nausea, vomiting, and hypotension. | — |
Countries
Nigeria
Contacts
Public ContactOlubunmi Tunde Olatunji
Medical Consultant
Outcome results
None listed