Post Cesearean setion pain Anaesthesia
Conditions
Interventions
Nefopam combined with Dexamethasone
Sponsors
Self
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: ? All ASA II and III patients at term gestation for elective Caesarean section under subarachnoid block. ASA II and III are contradictions to what are labelled as exclusion criteria (PUD, DM and uncontrolled hypertension) .
Exclusion criteria
Exclusion criteria: ? Patient’s refusal to give written informed consent. ? Patients with known allergy or sensitivity to the study medication ? Present or past history of peptic ulcer disease ? Contraindications to spinal anaesthesia ? Diabetes mellitus Type 1 or 2 ? Systemic infection, ? Patients with coexisting hepatic, renal, or cardiovascular disease. ? History of chronic pain. ? Opioid use 48hours preceding surgery. ? Antenatal diagnosis of foetal abnormality ? Known IV drug users. ? Glaucoma ? Liver cirrhosis ? Psychiatric illnesses ? Patients on antiviral medications or live vaccines ? Uncontrolled hypertension ? Requiring more than 100mg IV Tramadol for treatment of breakthrough pain
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome for the study was the proportion of patients scoring less than or equal to 3 using the NRS, at 6 and 12 hours after the administration of study drugs | — |
Secondary
| Measure | Time frame |
|---|---|
| a) Time to first analgesic request. The time from administration of study drugs to first analgesic request. b) Comparison of pain scores between the two groups in the first 24 hours postoperatively. c) Comparison of the Total analgesic consumption between the two groups in the first 24 hours postoperatively d) Comparison of Incidences of side effects related to study drugs such as nausea and vomiting and sedation | — |
Countries
Nigeria
Contacts
Public ContactChristian Igibah
Research Assistant at Department of Anaesthesia Irrua specialist teaching hospital
Outcome results
None listed