Skip to content

Randomised Controlled Trial: Intrauterine Misoprostol Versus Sublingual Misoprostol In The Prevention Of Postpartum Hemorrhage At Elective Caesarean Section At Korle Bu Teaching Hospital, Ghana.

Randomised Controlled Trial: Intrauterine Misoprostol Versus Sublingual Misoprostol In The Prevention Of Postpartum Hemorrhage At Elective Caesarean Section At Korle Bu Teaching Hospital, Ghana.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
PACTR
Registry ID
PACTR202309644870215
Enrollment
148
Registered
2023-09-28
Start date
2023-10-01
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postpartum haemorrhage

Interventions

Sponsors

Self sponsored DR CHIDINMA PEACE OHACHENU
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Pregnant women 18 years and above Singleton gestation Gestational age between 37 weeks 0 days to 41 weeks 3 days.

Exclusion criteria

Exclusion criteria: haemoglobin level 25cm or DVP >8cm) large uterine fibroid (at least one nodule with size >10cm) and/or any FIGO Type 0 fibroids post-placental IUCD insertion known coagulation disorders known allergy to Misoprostol.

Design outcomes

Primary

MeasureTime frame
The primary outcome measure is overall blood loss i.e., a combination of intraoperative blood loss and blood loss up to 3 hours after surgery. Intraoperative blood loss in this study will be defined as blood loss from after delivery of the placenta to the end of surgery.

Secondary

MeasureTime frame
change in the preoperative and postoperative haematocrit levels;side effects profile (fever, vomiting, and shivering);The need for additional PPH interventions which include additional uterotonic (Oxytocin, Ergometrine, carbetocin), tranexamic acid, uterine tamponade, compression sutures, artery ligation, hysterectomy at primary surgery, relaparotomy, and admission to ICU

Countries

Ghana

Contacts

Public ContactKwame Asah Opoku

Consultant Obstetrics and Gynaecology Korle Bu Teaching Hospital

kasahopoku@yahoo.com0242048236

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026