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A study comparing antimicrobial sutures with regular sutures in prevention of infection following cranial surgery

A comparative analysis of antimicrobial sutures and conventional sutures in the prevention of cranial surgical site infection

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
PACTR
Registry ID
PACTR202308874091441
Enrollment
100
Registered
2023-08-25
Start date
2023-09-01
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nervous System Diseases

Interventions

Regular vicryl sutures

Sponsors

Dr CHIZOWA OKWUCHUKWU EZEAKU
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients aged 2–80 years. Consenting patients who are scheduled for cranial surgical procedures under general anaesthesia requiring scalp incisions All patients for cranial surgical procedures with class I wounds as defined by the American College of Surgeons and without evidence of systemic focus of infection Patients with controlled comorbidities

Exclusion criteria

Exclusion criteria: Patients with an intracranial or systemic infection before the procedure Patients with contaminated or dirty surgical wounds Patients who die within 30 days after surgery from complications unrelated to SSIs Patients on long-term steroid use (> 1 month) or with uncontrolled co-morbidities Patients undergoing surgery with the use of implants

Design outcomes

Primary

MeasureTime frame
The primary outcome measure will be the surgical site infection rate reported by blinded assessors within 30 days of surgery, which will be compared in both groups.

Secondary

MeasureTime frame
The length of hospital stay in those with surgical site infection and the pattern of causative microorganism

Countries

Nigeria

Contacts

Public ContactCHIZOWA EZEAKU

DIVISION OF NEUROSURGERY OBAFEMI AWOLOWO UNIVERSITY HOSPITALS COMPLEX

ezeakuchizowa@gmail.com+2348080054944

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026