Circulatory System Injury, Occupational Diseases, Poisoning Cardiology
Conditions
Interventions
Blood samples for the measurement of BNP and troponin level will be obtained from the central line
Sponsors
Faculty of medicine Ain Shams University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1- Age: eligible = 21 - = 60 yrs. 2- Sex: eligible both sexes. 3- Patients with American Society of Anesthesiologists (ASA) physical status I-II. 4- Patients with Total Burn Surface area (TSBA) = 20% up to = 50% 5- Patients with 2nd degree burn or more.
Exclusion criteria
Exclusion criteria: 1- 60 years old. 2- Declining to give written informed consent. 3- Patients with preexisting cardiac or pulmonary diseases e.g., hypertension, congenital heart disease, ischemic heart disease with impaired cardiac function, valvular heart disease, heart failure, infective endocarditis. 4- Patients with severe hepatic impairment (INR = 1.5, Bilirubin = 2, Albumin = 2). 5- Patients with renal dysfunction (GFR < 50ml/min).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ?The primary outcome will be the sensitivity and specificity of the BNP plasma level as an early predictor of the incidence of toxic myocarditis | — |
Secondary
| Measure | Time frame |
|---|---|
| the secondary outcomes will be the incidence of other complications such as sepsis and other organ failure as well as ICU stay and total hospital stay. | — |
Countries
Egypt
Contacts
Public ContactMarwa Khairy
Assistant Professor at department of anasethsia faculty of medicine ain shams university
Outcome results
None listed