Nervous System Diseases
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) The patients with (L4, L5) (L5, S1) disc herniation with radiculopathy referred from neurological or orthopedic department after doing MRI of lumbar spine. 2) Patients age ranged from 30 -45 years old. 3) The duration from onset of pain was from 3-12 months. 4) The selected patients in the study were ambulant independently.
Exclusion criteria
Exclusion criteria: 1) Patients with any pathology preventing neural tissue testing (eg: restriction of joint range of motion, lumbar myelopathy, fracture, instability). 2) Patients with history of previous lumbar surgery, gross neurological deficits and inflammatory arthritis. 3) Patients with medical red flags as severe psychiatric disorder or cognitive deficits. 4) Medically unstable and uncooperative patients. 5) Causes of hyper cortisolism other than radiculopathy as diabetes, chronic renal failure, pituitary or adrenal gland tumor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measurement of serum cortisol level was done for each patient by using immulite ® 2000 systems analyzers. Measurement of pro inflammatory cytokines level was done for each patient by using Stat Fax 2100 Microplate Reader device. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain intensity Pain was assessed by using a visual analog scale (VAS).Functional ability was evaluated by Modified Oswestry Low Back Disability Questionnaire | — |
Countries
Egypt
Contacts
Lecturer at the neurological department Faculty of physical therapy Cairo University