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Pre-operative study the efficacy of nebulized Dexmedetomidine on blunting hemodynamic changes during intubation and pneumoperitoneum in morbid obese patients during laparoscopic bariatric surgery. Randomized double blind control study

Pre-operative study the efficacy of nebulized Dexmedetomidine on blunting hemodynamic changes during intubation and pneumoperitoneum in morbid obese patients during laparoscopic bariatric surgery. Randomized double blind control study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202308566462034
Enrollment
90
Registered
2023-08-23
Start date
2023-09-01
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

normal saline group
Dexmedetomidine group

Sponsors

sherif kamal hafez arafa
Lead Sponsor
sherif kamal hafez arafa
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1-This study will include 90 adult morbidly obese patients of both sex 2- with BMI (30-45), 3-ASA II-III physical status, 4-aged between 20-60 years 5- scheduled for elective laparoscopic bariatric surgery under general anesthesia.

Exclusion criteria

Exclusion criteria: 1-Patients' refusal 2-Decompansated hepatic or renal or cardiac disease 3-Expected difficult airway management 4-Uncontrolled hypertension 5-Psychiatric disease 6-Sever pulmonary disease 7-Patient om opioid, alcohol, beta0 blockers or allergy to any of the study drugs.

Design outcomes

Primary

MeasureTime frame
The primary outcome is hemodynamic response to intubation and pneumoperitoneum.—

Secondary

MeasureTime frame
-Preoperative sedation score -Intraoperative fentanyl consumption and propofol consumption for induction. -Time for first use of rescue analgesia postoperatively. -Total opioid consumption in the first 24 hours postoperative. -Any adverse effects as cough, bradycardia and hypotension.—

Countries

Egypt

Contacts

Public ContactAmir Abuzikary

assisstant professor of anesthesia and surgical ICU

aabozikry@yahoo.com00201016326544

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026