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Peri-operative vaginal cleansing using 4% chlorhexidine versus 10% povidone-iodine solution to prevent post-caesarean endometritis in Ilorin: A randomized controlled study

Peri-operative vaginal cleansing using 4% chlorhexidine versus 10% povidone-iodine solution to prevent post-caesarean endometritis in Ilorin: A randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202308561344907
Enrollment
136
Registered
2023-08-03
Start date
2023-02-06
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometritis Peuperial infection

Interventions

chlorhexidine
Povidoneiodine

Sponsors

Nasiru Ibrahim Orisankoko
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Women aged =18 years scheduled for non-elective CS irrespective of the booking status. Live intrauterine fetus (es). Consent to participate in the study

Exclusion criteria

Exclusion criteria: Active genital warts. Women with antepartum haemorrhage or an ongoing episode of vaginal bleeding. Reported allergy to chlorhexidine and / or iodine containing solution. Women previously on antibiotic therapy for more than 24hours before surgery irrespective of the indication. Women with fetus (es) with face presentation. Women with clinical diagnosis of chorioamionitis.. Women with diagnosed thyroid disorders or goitre on examination.

Design outcomes

Primary

MeasureTime frame
The primary outcome of this study will be the incidence of endometritis (both clinical and laboratory) for women who had vaginal cleansing with 4% Chlorhexidine (experiment group) and 10% PVP-I (control).

Secondary

MeasureTime frame
secondary outcomes to be measured for the study are: Presence of adverse reaction to the vaginal cleansing agent (vaginal dryness, burning sensation, vaginal itching, vulva rashes, vulva swelling, and vulva pain). Clinical evidence of post-operative wound infection. Relationship between risk factors for endometritis and occurrence of endometritis. Neonatal outcomes especially first and fifth-minute APGAR scores as well as admission into Neonatal intensive care unit (NICU).

Countries

Nigeria

Contacts

Public ContactNasiru IBRAHIM

Senior Resident Doctor

nasiruibrahim424@gmail.com+2347037957122

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026