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Comparison of the effects of three agents used in the treatment of disease of the pulp in permanent posterior teeth in the Nigerian adult population

A comparative evaluation of three indirect pulp capping agents in the treatment of reversible pulpitis in permanent posterior teeth in Nigerian adult patient

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
PACTR
Registry ID
PACTR202308547851267
Enrollment
150
Registered
2023-08-08
Start date
2019-08-21
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Health

Interventions

Group A or calcium hydroxide group
Group B or Mineral trioxide aggregate group
Group C or Biodentine group

Sponsors

Igweagu Chibuzor Emmanuel
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Individuals who are eighteen years and above 2. Premolar and(or) molar teeth with active deep carious lesions of GV Black Class I or II configurations 3. Teeth with the above characteristics with mild provoked intermittent pain 4. Teeth with positive electric and cold thermal sensibility test that ceased within fifteen seconds of removal of stimulation 5. Teeth with radiographic evidence of carious lesion extension into the pulpal quarter of the dentine thickness without pulpal communication 6. Teeth with periapical index of two or less 7. Teeth from individuals with the above characteristics who had not consumed any antibiotics within the preceding two months to recruitment

Exclusion criteria

Exclusion criteria: 1. Teeth with arrested carious lesions 2. Teeth with advanced periodontal disease or periodontal-endodontic lesions 3. Teeth with radiographic evidence of periapical pathology or partial or complete pulpal obliteration 4. Unrestorable or grossly broken teeth with reversible pulpitis 5. Teeth with signs and symptoms of irreversible pulpitis , acute or chronic apical periodontitis

Design outcomes

Primary

MeasureTime frame
Clinical outcome by conducting sensibility test, periapical palpation test, percussion test, mobility test and denoting the presence or absence of pain at 1,3, and 6 months post-operative period. Radiological outcome were determined by measuring the thickness of reparative dentine formed at 3 and 6 months

Secondary

MeasureTime frame
The influence of age, gender and site of carious lesion on treatment outcome

Countries

Nigeria

Contacts

Public ContactChibuzor Igweagu

Head

cigweagu@gmail.com2348023019448

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026