Targeted Fluid Resuscitation in Septic Shock: A Comparative Study between Capillary Refilling Time and Venous to Arterial PCO2

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202307764415273

Enrollment

Registered

2023-07-18

Start date

2022-09-21

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

management of septic shock patients in ICU

Interventions

capillary refill time as prognostic

Venous to Arterial PCO2 difference measurement

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: • Adult patients (aged 21-60 years) with septic shock. • Serum lactate>2 mmol/liter. • Requirements of norepinephrine (NE) to maintain a mean arterial pressure (MAP)=65 mmHg after an intravenous fluid load of 20 ml/kg over 60 min. • Patients had to be recruited within a period of 24 h after septic shock diagnosis.

Exclusion criteria

Exclusion criteria: • Pregnancy. • Peripheral vascular disease. • Anticipated surgery or dialysis. • Procedure during the first 6 h after potential inclusion. • Active bleeding. • Child B or C liver cirrhosis. • Severe acute respiratory distress syndrome (ARDS).

Design outcomes

Primary

Measure	Time frame
Serum lactate measurement within ,first 6 hours intervention period	—

Secondary

Measure	Time frame
1- 24 h SOFA score. 2. fluid volume administrated during the 6 hours intervention period	—

Countries

Egypt

Contacts

Public ContactMostafa ryad

professor

drmkamel2002@gmail.com01270742475

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026