HIV/AIDS
Conditions
Interventions
Covi soup alongside Standard care
Standard care
Sponsors
Masinde Muliro University of Science and Tachnology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: PLWH aged 15-65 years. PLWH on anti-HIV drugs for a maximum of five years. PLWH adhering to anti-HIV treatment for the past 3 years. PLWH with a CD4+ cell count >200cells/microliter of blood. PLWH who give informed consent. PLWH attending the Kakamega County Teaching and Referral Hospital CCC from the same household.
Exclusion criteria
Exclusion criteria: PLWH on other medications other than ARTs. PLWH on ARVSaquinavir and Ritonavir. Pregnant and Lactating women living with HIV. PLWH with CD4+ cell count >200cells/microliter of blood who are severely ill.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CD4 cell count. These are a type of immunological cells that are greatly affected by the HIV. They are used as markers for disease progression. WHO CD4 ranges are used to define the clinical stage of HIV infection. This study seeks to establish the effect of Covi soup on the CD4 count of PLWH in Kakamega county, Kenya.;No of Viral Load in copies per milliliter of blood. VL is used to determine disease progression and adherence to drugs. This study will determine the effect of Covi soup on the VL.;Hb in grams per deciliter. Decreased Hb indicates iron deficiency anemia which is a marker of disease progression. The study will determine the effect of Covi on the Hb level of PLWH in Kakamega county. Hb less than 12.0g/dl will be defined as anemic in both men and women. ;Mean Corpuscular Volume in femtoliters. Low MCV indicates microcytic anemia due to iron deficiency, High MCV indicates macrocytic anemia due to low folate and vitamin B12. The study will determine effect of Covi soup on MCV of PLWH in Kakamega county. ;Mean Corpuscular Hemoglobin in picograms. Hypochromic anemia indicates iron deficiency anemia, hyperchromic anemia means deficiency of vitamin B12 and folate. The study seeks to find out the effect of Covi soup on the MCH level of PLWH in Kakamega county. ;Mean Corpuscular Hemoglobin Concentration in percentage. Hypochromic anemia is a sign of iron deficiency anemia and hyperchromic anemia indicates hymolytic anemia. This study will investigate the effect of Covi soup on the MCHC level of PLWH in Kakamega county. ;Body mass index an anthropometric measure that will be used to describe the nutrition status of the study participants. BMI is used to predict the HIV progression. Increased BMI is associated with cardiovascular diseases that are risk factors to COVID 19 infection. Decreased BMI is also associated with immune suppression that increases susceptibility to co infections like COVID 19. Hence, in this study seeks to determine whether Covi soup can h | — |
Secondary
| Measure | Time frame |
|---|---|
| Nutrition status. The study will investigate whether Covi soup has an effect on the nutrition status of PLWH. Good nutrition status is important to slow the disease progression in HIV by reducing the risk of getting opportunistic and co infections such as Covi soup.;Immune status which will be determined by CD4 cell count and VL.;Hematological status of PLWH in which the Hb, MCV, MCH and MCHC will be measured. | — |
Countries
Kenya
Contacts
Public ContactAntonette Kivelenge
Trainer of Nutrition and Dietetics
Outcome results
None listed