Chronic hypertension in Pregnancy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: All consenting pregnant women aged 18-49 years who have chronic hypertension (sustained systolic blood pressure of >/= 140/90 mmHg, present at booking or before 20 weeks gestation, or receiving anti-hypertensives before pregnancy)
Exclusion criteria
Exclusion criteria: - Pregnancy-induced hypertension - Preeclampsia/ eclampsia - Diabetes mellitus - Thyroid disorders - SLE - Hyperlipidemia - Chronic kidney disease - Chronic liver disease - Sickle cell disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| •Participant recruitment rates •Participant retention rates •Fidelity to the protocol •Acceptability | — |
Secondary
| Measure | Time frame |
|---|---|
| • Mean change in systolic BP from enrollment to 6 weeks post delivery • The proportion of participants who achieve BP control (<140/90 mm Hg);• The rate of Adverse maternal outcomes (defined as pre-eclampsia, eclampsia, cesarean section, and mortality) • The rate of adverse perinatal outcome (defined as IUGR, IUFD, preterm delivery, NICU admission, perinatal deaths) | — |
Countries
Ghana, Nigeria
Contacts
Consultant Cardiologist