Caffeine versus Dexmedetomidine for the prevention of emergence delirium in children undergoing lower abdominal surgery with sevoflurane anesthesia: a randomized, double-blind, controlled study

Caffeine or Dexmedetomidine for the prevention of emergence delirium in children undergoing lower abdominal surgery with sevoflurane anesthesia: a randomized, double-blind, controlled study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202306816155472

Enrollment

Registered

2023-06-08

Start date

2023-06-15

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Paediatrics Anaesthesia

Interventions

the control Dexmedetomidine group 1

caffeine group 2

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Children aged between 2-84 months American Society of Anesthesiologists physical status I or II undergoing scheduled elective unilateral inguinal hernia repair

Exclusion criteria

Exclusion criteria: previous inguinal surgery, history of clinically significant cardiac, hepatic, renal, or neurological dysfunction, coagulopathy, known allergy to drugs.

Design outcomes

Primary

Measure	Time frame
ED will be assessed by upon extubation and every 5 minutes thereafter until 30 minutes after extubation	—

Secondary

Measure	Time frame
postoperative FLACC pain score ;Hemodynamic parameters such as heart rate (HR), systolic blood pressure (SBP), and diastolic blood pressure (DBP) ;Extubation time;PACU length of stay after extubation ;adverse events such as PONV, laryngospasm, severe coughing, oxygen desaturation	—

Countries

Egypt

Contacts

Public ContactIbrahim Abdelbaser

Assistant professor of anesthesiafaculty of medicine Mansoura universityEgypt.

ibrahimbaser2010@yahoo.com+201004976825

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026