Mental and Behavioural Disorders
Conditions
Interventions
BLENDED MOTIVATIONAL INTERVIEWING AND COGNITIVE BAHAVIOURAL THERAPY
Sponsors
NIH
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: HIV infected male and female participants; aged 18-24 years; documentation of HIV infection from local standard of care; HIV viral load >200 copies/ml; Problematic use of alcohol/substance or risk of alcohol/substance use shown by an Alcohol Use Disorders Identification Test (AUDIT) score of at least 6 for female participants and at least 7 for male participants or a Drug Use Disorders Identification Test (DUDIT) score of 2 or more for female participants and 6 or more for male participants; Current poor adherence to ART as noted by the HIV/ART care provider and measured by pill count; Able and willing to give informed consent
Exclusion criteria
Exclusion criteria: Age less than 18 years of greater than 24 years; Unable or unwilling to give informed consent; Viral load <200 copies/ml; No history of alcohol or substance use
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Viral load suppression as defined by viral load<20 copies/ml measured at 24 weeks after initiation of the behavioral intervention. Tenofovir drug levels in hair samples demonstrating adherence to ART. | — |
Secondary
| Measure | Time frame |
|---|---|
| Score demonstrating the reduction in substance use eg reduction in Alcohol Use Disorders Identification Test (AUDIT) /Drug use disorders identification test (DUDIT) score. | — |
Countries
Zimbabwe
Contacts
Public ContactPamela Mukwekwerere
University of Zimbabwe Clinical Trials Research Centre
Outcome results
None listed