A comparison of the efficacy of two and three passes of vaginal cleansing with chlorhexidine or placebo before emergency caesarean section in reducing infectious morbidity

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202306725476304

Enrollment

162

Registered

2023-06-01

Start date

2023-05-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy and Childbirth Surgery

Interventions

Preoperative vaginal cleansing with sterile water

Two passes of preoperative vaginal cleansing

Three passes of preoperative vaginal cleansing

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Inclusion criteria Pregnant women at 28 weeks gestational age or more with indications for emergency caesarean section who will consent to the study will be recruited.

Exclusion criteria

Exclusion criteria: Exclusion criteria 1. Placental praevia 2. Clinical chorioamnionitis 3. Allergy or contraindication to Chlorhexidine 4. Allergy or contraindication to Ceftriaxone 5. Cord prolapse 6. Pre-exiting medical conditions such as severe anaemia, uncontrolled DM and HIV with unsuppressed viral load 7. Gestational age < 28 weeks 8. Caesarean hysterectomy 9. Elective caesarean section

Design outcomes

Primary

Measure	Time frame
The primary outcome measure will be endometritis	—

Secondary

Measure	Time frame
The secondary outcome measure will be superficial surgical site infection.	—

Countries

Nigeria

Contacts

Public ContactEse Adigba Onodjohwoyovwe

Senior Registrar Federal Medical Centre

adigbaese@gmail.com234868115905

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026