Malaria
Conditions
Interventions
Housing improvement
Ivermectin administration to cattle
Combination of house improvment and ivermectin administration to cattle
Basic malaria interventions like ITNs
Sponsors
The Norwegian Programme for Capacity Development in Higher Education and Research for Development.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All households and members in the clusters assigned to either of the interventions or control and willing to sign informed consent to participate in the malaria study for two years will be included. Villages close to the shores of the two Rift Valley lakes and endemic for malaria will be included in the study to minimize the variation between villages. The flight distance of mosquitoes will be considered in selecting clusters for the study to reduce the diversion effect of the intervention and contamination due to mosquito movement. All cattle except lactating cows and those planned to be used for meat in the near future will be involved in the study.
Exclusion criteria
Exclusion criteria: Those households that refuse to participate in the study or whose house structures are unsuitable for screening will be excluded. Children below one year will not been enrolled in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Malaria incidence in all age groups above 1 year Prevalence of malaria in all age groups above 1 year | — |
Secondary
| Measure | Time frame |
|---|---|
| • indoor and outdoor density of malaria mosquitoes • prevalence of antibody against salivary gland antigens • seroprevalence of malaria parasites • cost-effectiveness of the intervention • household multidimensional poverty reduction • prevalence of gametocyte carriage in human hosts • parasite density of symptomatic and asymptomatic malaria cases • prevalence of anemia in children age between1-5 years • spatio-temporal clustering of malaria in control and intervention arms • sporozoite infection rate • entomological inoculation rate • blood meal index • mosquito biting rates • proportion of freshly fed mosquitoes with gametocyte • malaria sero-conversion rate among children • effectiveness of serological biomarkers in monitoring vector control • community acceptance of the intervention • durability of house screening • ITNs use rate • human night activities and sleeping patterns (time) | — |
Countries
Ethiopia
Contacts
Public ContactAlemayehu Chufama
Vice President for Academic Affairs
Outcome results
None listed