Assessment of fluid responsiveness in septic shock patients
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: age 21-60 years old both sexes Septic hypotensive patients sedated intubated on controlled mechanical ventilation with no respiratory effort. in need of intravenous fluid administration for resuscitation according to the clinical presentation (systolic arterial blood pressure (BP) 20 mmHg from the baseline of MAP, or with signs of hypoperfusion including oliguria less than 0.5 ml/kg/h and arterial lactate > 2.5 mmol/L).
Exclusion criteria
Exclusion criteria: Spontaneous breathing poor cardiac echogenicity cardiac arrhythmia Severe valvular heart disease / intracardiac shunt impaired left ventricular function with ejection fraction < 40% ascites pregnancy malignancy congestive heart failure Evidence of fluid over-load renal dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in COP after fluid therapy using ECHO , Predictive value of EEO and IVC respiratory variation to fluid responsiveness in septic mechanically ventilated patients | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in blood pressure in response to fluid therapy Changes in heart rate in response to fluid therapy | — |
Countries
Egypt
Contacts
lecturer of anesthesia Department of Anesthesia Intensive Care and Pain Management FACULTY OF MEDICINE Ain Shams University Cairo Egypt