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The use of End Expiratory Occlusion Test vs. Inferior Vena Cava Respiratory Variation for prediction of volume responsiveness in mechanically ventilated patients with sepsis

The use of End Expiratory Occlusion Test vs. Inferior Vena Cava Respiratory Variation for prediction of volume responsiveness in mechanically ventilated patients with sepsis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202306581320725
Enrollment
34
Registered
2023-06-08
Start date
2023-03-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Assessment of fluid responsiveness in septic shock patients

Interventions

IVC respiratory variation
VTI after Fluid therapy

Sponsors

Faculty of medicine Ain Shams university
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: age 21-60 years old both sexes Septic hypotensive patients sedated intubated on controlled mechanical ventilation with no respiratory effort. in need of intravenous fluid administration for resuscitation according to the clinical presentation (systolic arterial blood pressure (BP) 20 mmHg from the baseline of MAP, or with signs of hypoperfusion including oliguria less than 0.5 ml/kg/h and arterial lactate > 2.5 mmol/L).

Exclusion criteria

Exclusion criteria: Spontaneous breathing poor cardiac echogenicity cardiac arrhythmia Severe valvular heart disease / intracardiac shunt impaired left ventricular function with ejection fraction < 40% ascites pregnancy malignancy congestive heart failure Evidence of fluid over-load renal dysfunction.

Design outcomes

Primary

MeasureTime frame
Changes in COP after fluid therapy using ECHO , Predictive value of EEO and IVC respiratory variation to fluid responsiveness in septic mechanically ventilated patients

Secondary

MeasureTime frame
Changes in blood pressure in response to fluid therapy Changes in heart rate in response to fluid therapy

Countries

Egypt

Contacts

Public ContactAhmad Moneer Ahmad Youssef Eldemerdash

lecturer of anesthesia Department of Anesthesia Intensive Care and Pain Management FACULTY OF MEDICINE Ain Shams University Cairo Egypt

Ahmedmonier@med.asu.edu.eg0020201114959206

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026