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Combined Adductor Canal and Infiltration in the Space between Popliteal Artery and Posterior Capsule of the Knee Blocks (IPACK) Versus Combined Genicular Nerve Block and Infiltration in the Space between Popliteal Artery and Posterior Capsule of the Knee Block (IPACK) in Total Knee Arthroplasty.

Combined Adductor Canal and Infiltration in the Space between Popliteal Artery and Posterior Capsule of the Knee Blocks (IPACK) Versus Combined Genicular Nerve Block and Infiltration in the Space between Popliteal Artery and Posterior Capsule of the Knee Block (IPACK) in Total Knee Arthroplasty.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202305870625335
Enrollment
40
Registered
2023-05-09
Start date
2022-11-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

Genicular nerve block combined with IPACK block

Sponsors

Sara Magdy Abdelrhman Elkfafi
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: - American Society of Anaesthesiologists (ASA) physical status I–III. - Patients between the ages of 18 and 80 years. - Patients undergoing primary unilateral knee arthroplasty. - Both sexes. - BMI = 40

Exclusion criteria

Exclusion criteria: - Patient’s refusal to be enrolled in the study. - Bilateral TKA or previous surgery on the same knee. - Allergy to one of the study drugs. - Chronic use of gabapentin/pregabalin. - History of Arrhythmia, seizures or sepsis

Design outcomes

Primary

MeasureTime frame
-Time to the first rescue analgesic dose by assessing postoperative pain using NRS

Secondary

MeasureTime frame
- The total amount of Nalbuphine consumption , Hemodynamic changes ,The patient’s first mobilization time will be recorded in hours, Timed Up and Go (TUG test), side effects of nerve blocks and the length of hospital stay

Countries

Egypt

Contacts

Public ContactReham Mustafa Hashim Kotb

Assistant Professor of Anesthesia and ICU and Pain Management

Dr_reham80@yahoo.com01003072065

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026