Vaginal douching with acetic acid versus normal saline prior to pre-induction cervical ripening with intravaginal misoprostol among nulliparous women at term: A randomized study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202305683057580

Enrollment

170

Registered

2023-05-05

Start date

2023-05-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CERVICAL RIPENING AND INDUCTION OF LABOUR

Interventions

Normal saline

5 percent acetic acid

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Term (37 to 42weeks) singleton pregnancy Nulliparity Cephalic presenting fetus No drainage of liqour No contraindication to vaginal delivery

Exclusion criteria

Exclusion criteria: Preterm pregnancy Intra uterine fetal death Cephalopelvic disproportion Fetal abnormal lie Fetal abnormal presentation Multiple pregnancy Previous caesarean scar or uterine surgeries Preinduction fetal heart rate abnormalities Present history of antepartum haemorrhage

Design outcomes

Primary

Measure	Time frame
The mean time from administration of intravaginal misoprostol to active phase of labour.	—

Secondary

Measure	Time frame
Mean total doses of misoprostol administered for preinduction cervical ripening in each group Proportion of women that had need for oxytocin induction The mean time from administration of intravaginal misoprostol to vaginal delivery (induction-delivery interval). Proportion of neonates with birth asphyxia (Apgar score less than 7 in 1 minute) in each group.	—

Countries

Nigeria

Contacts

Public ContactCHIDIMMA OKAFOR

Public Enquiries

favourspecialist2020@gmail.com+2347069099217

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026