Mental and Behavioural Disorders
Conditions
Interventions
Mild cognitive impairment group
Placebo
Sponsors
WESTERN SYDNEY UNIVERSITY
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: • The subject is between 50-75 years old. • The subject is clinically diagnosed with Mild cognitive impairment by the Neurologist. • The subject's MoCA score is between 10-26. • The subject can cooperate to perform cognitive function tests. • The subject has dependable caregivers who can record the compliance of taking probiotics and any physical conditions. • The subject or family members signed the informed consent form and answered the questionnaire.
Exclusion criteria
Exclusion criteria: • The subject has dementia caused by other reasons, such as brain trauma, tumour, infection, epilepsy, etc. • The subject has consumed probiotic-related products (probiotic powder, yoghurt or other fermented foods) within the past 1 month. • The subject has participated in clinical trials of other dementia medications in the past 1 month. • The subject is assessed for dementia caused by vitamin B12 deficiency or thyroid abnormalities. • The subject suffers from mental illness, severe depression, schizophrenia, drug addiction, and alcohol addiction. • The subject has Parkinson's disease. • The subject is assessed to have severe metabolic and liver and kidney dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ?cognitive function measured using an appropriate, validated cognitive test, gut microbiota diversity and composition | — |
Secondary
| Measure | Time frame |
|---|---|
| ? changes in metabolic variables, Biomarkers and cognitive function ? Randomized controlled trials (RCTs) and clinical controlled trials (CCTs) | — |
Countries
Ghana
Contacts
Public ContactPatrick Adjei
Head of Medicine department of Korle Bu Teaching Hospital
Outcome results
None listed