postoperative intrathecal analgesia for lumber spine surgery

Efficacy and safety of preemptive intrathecal morphine versus nalbuphine in lumbar spine surgery: A randomized clinical trial.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

PACTR

Registry ID

PACTR202304865602085

Enrollment

Registered

2023-04-04

Start date

2023-05-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Musculoskeletal Diseases Surgery

Interventions

intrathecal morphine

intrathecal nalbuphine

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: both sex ASA physical status I &II age range 30-60 years old scheduled to undergo elective open posterior lumbar interbody fusion surgery at 1 or 2 level

Exclusion criteria

Exclusion criteria: • Body mass index >35 kg/m2. • Patients with neurological deficit (symptoms of lumbar intervertebral nerve injury (determined by a neurosurgical specialist based on physical and imaging examinations). • Redo or previous lumber surgery. • Allergy or contraindication to the given study drugs. • Patients on chronic pain medication. • Chronic alcoholism, history of a major psychiatric disorder or cognitive disorder (inability to understand the VAS). • Any contraindication to intrathecal injection.

Design outcomes

Primary

Measure	Time frame
The duration of effective analgesia	—

Secondary

Measure	Time frame
pain score ;adverse effects e.g. PONV, pruritus, respiratory depression, urinary retention, sedation ;postoperative fentanyl consumption	—

Countries

Egypt

Contacts

Public ContactNashwa Hamoda

lecturer

Nashwa741987@gmail.com+201020526560

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026