Helicobacter Pylori
Conditions
Interventions
Standard therpy group
Study group
Sponsors
Theodor BIlharz REasearch Institute
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Symptomatic patients who were positive H Pylori stool antigen and had never been treated for H.Pylori.
Exclusion criteria
Exclusion criteria: Patients below 18 years or above 80 years of age previously received H. pylori eradication therapy use of antimicrobials or medications that might interfere with H Pylori stool antigen detection( like PPI or H2 blockers use within the previous 2 weeks of stool testing) previous incidents of gastric or duodenal bleeding, gastric surgery, gastric malignancy, or other life-threatening conditions unwilling to give consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study the impact of adding probiotics to standard triple therapy for achieving better H. pylori eradication rates compared to standard triple therapy alone. | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the role of probiotics in the correction of gut dysbiosis after eradication therapy To study the side effects of antibiotics in the probiotics receiving group versus the other group To assess obesity as a variant factor that might affect the acquisition of H Pylori infection, response to standard triple therapy and effect of adding probiotics to modify treatment response | — |
Countries
Egypt
Contacts
Public ContactMohamed Dewidar
Assistant Researcher Hepatology and gastroenterology TBRI
Outcome results
None listed