Fertility-male
Conditions
Interventions
Zinc Sulfate
Sponsors
Sadiya Musa Gwadabe
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Male partners of infertile couple within the age of 20-59years having regular unprotected intercourse for a year or more. 2. Men with sperm concentration <15million cells/ml on two occasions 4 weeks apart. 3. Male partners with normal descended testes. 4. Patient who consent to participate in the study
Exclusion criteria
Exclusion criteria: 1. Men with the following problems will be exckuded:Aspermia, azoospermia, testicular varicocele, ongoing sexually transmitted disease, chronic illness, serious systemic disease like diabetes, endocrine and metabolic disorders, smoking, alcohol intake and previous groin or scrotal surgery 2. Men that have used zinc within three months of recruitment /other supplements 3. Men on drugs that suppress spermatogenesis such as steroidsand other immunosuppressive drugs 4. Men with immunosuppressive disease like Human Immunodeficiency Virus (HIV) and malignancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Baseline seminal and serum zinc levels 2. Serum and seminal zinc level after administration of zinc sulphate or placebo. 3. Baseline sperm count 4. Sperm count after administration of zinc sulphate or placebo | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Semen parameters (Concentration, motility, morphology and volume) after administration of zinc sulphate and placebo. 2. Adverse effects of the Intervention drug reported by the patients. | — |
Countries
Nigeria
Contacts
Public ContactKike Adesina
Consultant Obstetrics and Gynaecology
Outcome results
None listed