Respiratory
Conditions
Interventions
Dexamethasone
Placebo
Sponsors
Shittu khadijah
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All consenting pregnant women at the General Hospital Ifako Ijaye with gestational age between 34+0 and 36+6 weeks, who were at high risk of delivering before 37 weeks. A high probability of preterm delivery includes; Women with intact membranes and at least 3 cm dilation or 75% effacement of the cervix Spontaneous rupture of the membranes Expected preterm delivery for any other indication by induction of labour or caesarean section.
Exclusion criteria
Exclusion criteria: All pregnant women with multiple pregnancy; Suspected or diagnosed major congenital malformations; Uncertain gestational age Clinical evidence of chorioamnionitis; Previous corticosteroid use during the antenatal period A woman who is expected to deliver in less than 12 hours. Women who were discharged from the hospital while still pregnant and who went on to deliver elsewhere were excluded from the study after randomization.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Presence of neonatal respiratory morbidity. These include: Respiratory distress syndrome; Transient tachypnea of the newborn and the need for ventilatory support within 72 hours of delivery with supplemental oxygen for at least 2 hours. Any neonate who had any of the 3 conditions is said to have had a respiratory morbidity. | — |
Secondary
| Measure | Time frame |
|---|---|
| These include: type of delivery; gestational age at birth; Apgar Scores at first and fifth minutes; admission to the Special Care Baby Unit (SCBU); neonatal hypoglycemia; neonatal jaundice; neonatal sepsis; other neonatal morbidities; length of stay at the hospital; neonatal death within 72 hours of delivery; the need for resuscitation at birth and feeding difficulties. | — |
Countries
Nigeria
Contacts
Public ContactKabiru Rabiu
LASUTH IKEJA LAGOS
Outcome results
None listed