Eye Diseases
Conditions
Interventions
SELECTIVE LASER TRABECULOPLASTY WITH ZEISS SLT LASER
Sponsors
None listed
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with primary open angle glaucoma or ocular hypertension. Patients who had the SLT procedure in the period from May to December 2022 Must have at least 3 months follow up after SLT. Patients who are on one or more topical intraocular pressure (IOP) lowering agent prior to SLT treatment, or treatment naïve patients who received SLT as primary intervention prior to commencing IOP treatment.
Exclusion criteria
Exclusion criteria: Patients who did not attend at least a 3-month follow-up after SLT. Patients with poorly controlled glaucoma who required surgery as primary intervention at the time of assessment, even though they may have still received SLT. Patients who had any ocular surgery during the period of the chart review. Previous successful or failed glaucoma surgery performed less than a year before the SLT procedure. Patients who had previous SLT laser. Abnormal angle anatomy that may have a degree of combined open and closed angle glaucoma. Anterior chamber angle Schaffer grade 1 or 2. Congenital glaucoma, neovascular glaucoma or uveitic glaucoma. Patients under the age of 18. Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary 1: To investigate whether ZEISS SLT decreased the number of IOP lowering agents required at 3, and 6 months after procedure, in glaucoma patients who are well controlled with medical therapy. (Subset A) 2: To describe the proportion of patients whose IOP reduced by >20% at 3 and 6 months after ZEISS SLT laser, in those patients who did not meet their target IOP on current medical treatment. (Subset B) 3: To estimate by how much the ZEISS SLT can reduce the IOP at 3 and 6 months after the procedure compared to baseline in those patients who did not meet their target IOP on current medical treatment. (Subset B) 4: To describe the proportion of patients whose IOP reduced by >20% at 3 and 6 months after ZEISS SLT laser, in newly diagnosed and treatment naïve glaucoma patients. (Subset C) 5: To estimate by how much the IOP was reduced at 3 and 6 months after ZEISS SLT laser compared to baseline, in newly diagnosed and treatment naïve glaucoma patients. (Subset C) | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary: 6: To describe the safety of the ZEISS SLT and any complications which may have occurred following the procedure. 7: To determine if there are any pre-procedural factors that may predict the efficacy of the SLT laser (e.g. demographics, anterior chamber angle characteristics, previous surgery or baseline IOP) | — |
Countries
South Africa
Contacts
Public ContactBrian Church
Specialist Ophthalmologist
Outcome results
None listed