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A randomized double-blinded clinical trial to investigate the role of ultrasound-guided transversus abdominis plane block

A randomized double-blinded clinical trial to investigate the role of ultrasound-guided transversus abdominis plane block after a radical hysterectomy of cervical cancer

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
PACTR
Registry ID
PACTR202303539794048
Enrollment
60
Registered
2023-03-03
Start date
2023-07-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer Surgery Anaesthesia

Interventions

TAP block with bupivacaine
TAP block

Sponsors

Bahir Dar University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: All adults aged greater than 18 years old with the following criteria will be considered. • Patients with the classification of ASA physical status II and III • Patients who can tolerate a general anesthetic • Patients undergoing cervical cancer surgery (radical hysterectomy) under general anesthesia, • Patients who can provide informed consent for the surgery • 20 ml of 0.25 % bupivacaine will be given for cases (TAP block) at the end of the surgery • Patients' weights are between 40-80 kg. • Patients who can provide informed consent for the surgery

Exclusion criteria

Exclusion criteria: • Patients who have bleeding disorders • Patients who are GCS <15 • Communication failure • Patients who have an allergy to local anesthetics • Patients who have multiple site surgery (outside of abdomen) • Patients who have underlying cardiovascular diseases • Patients with chronic pain and opioid use (using oral morphine greater than 100 mg daily).

Design outcomes

Primary

MeasureTime frame
The primary endpoint is postoperative pain which a numerical rating scale will assess

Secondary

MeasureTime frame
Total postoperative analgesic consumption: the total amount of analgesic requirement within the given postoperative period Time for first-time analgesic request: the initial time in which the patient feels pain and asks for analgesia Complications: any adverse events reported after surgery

Countries

Ethiopia

Contacts

Public ContactEyaya Misgan

associate professor

eyayamisgan@gmail.com+251913093115

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026