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MANAGEMENT OF PRIMARY PTERYGIUM: EVALUATING THE COMPARATIVE EFFICACY AND SHORT-TERM OUTCOMES OF INTRALESIONAL MITOMYCIN C TO INTRALESIONAL INTERFERON ALPHA-2B AT THE EYE CLINIC OF LAGOS STATE UNIVERSITY TEACHING HOSPITAL, IKEJA

MANAGEMENT OF PRIMARY PTERYGIUM: EVALUATING THE COMPARATIVE EFFICACY AND SHORT-TERM OUTCOMES OF INTRALESIONAL MITOMYCIN C TO INTRALESIONAL INTERFERON ALPHA-2B AT THE EYE CLINIC OF LAGOS STATE UNIVERSITY TEACHING HOSPITAL, IKEJA

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
PACTR
Registry ID
PACTR202302902720138
Enrollment
100
Registered
2023-02-15
Start date
2023-02-20
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eye Diseases

Interventions

Intralesional mitomycin C in grades 1 and 2 primary pterygium
Intralesional injection of interferon alpha2b in grades 1 and 2 primary pterygium

Sponsors

Dr. Maryam Fashola
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with grades 1 and 2 primary pterygia who present to the eye clinic of LASUTH within the period of study. 2. Consenting patients 3. Patients above 18 years (legal age for consent in Nigeria)

Exclusion criteria

Exclusion criteria: 1. Patients with recurrent pterygium. 2. Patients with a history of corneal trauma, ulcer or corneal surgery. 3. Patients with bipolar pterygium. 4. Pregnant and lactating patients. 5. Patients with a visual impairment from other causes e.g., cataracts, glaucoma.

Design outcomes

Primary

MeasureTime frame
Reduction in size of pterygium—

Secondary

MeasureTime frame
Reduction in vascularization;Improvement in refraction and keratometry;Improvement/resolution of dry eye symptoms—

Countries

Nigeria

Contacts

Public ContactMaryam Fashola

Senior Registrar Ophthalmology National Postgraduate Medical college of Nigeria

maryambo02@gmail.com+2348033648954

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026