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Role of Milrinone in the Prevention of Septic Myocardial Dysfunction in Pediatric Severe Sepsis and Septic Shock

Role of Milrinone in the Prevention of Septic Myocardial Dysfunction in Pediatric Severe Sepsis and Septic Shock

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202302881132303
Enrollment
40
Registered
2023-02-22
Start date
2023-02-15
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Paediatrics Cardiology

Interventions

Milrinone
Survival Sepsis Campaign

Sponsors

Pediatric Department Alexandria University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: - Children with severe sepsis/septic shock after resuscitation according to pediatric 2020 surviving sepsis campaign international guidelines( SSC) - Children with a cardiac index of more than 2.2 l/min/m2.

Exclusion criteria

Exclusion criteria: - Patients with primary myocardial diseases or congenital heart or chronic heart disease. - Patients with significant left ventricular outflow tract obstruction or the need for extracorporeal membrane oxygenation. - Patients receiving chemotherapeutic agents.

Design outcomes

Primary

MeasureTime frame
Development of low cardiac output syndrome ;Death

Secondary

MeasureTime frame
Duration of Pediatric Intensive Care Unit stay ;Duration of mechanical ventilation

Countries

Egypt

Contacts

Public ContactElsayedamr Basma

Patient Information Manager

elsayedamr@yahoo.com00201223106023

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026