difference between high intensity interval and moderate intensity continous intradialytic exercise on muscle quality index in hemodialysis patient

INTERVAL VERSUS CONTINOUS INTRADIALYTIC TRAINING ON MUSCLE QUALITY INDEX AND FUNCTIONAL CAPACITY IN HEMODIALYSIS PATIENTS

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

PACTR

Registry ID

PACTR202302873028626

Enrollment

Registered

2023-02-01

Start date

2023-01-10

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Musculoskeletal Diseases Kidney Disease

Interventions

high intensity interval aerobic exercise

moderate intensity continous aerobic exercise

no intervention

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: All patients will be included if they meet the following criteria: 1. Age between 45– 55 years. 2. Male sex included. 3. Patients with grade 5 chronic renal failure on hemodialysis. 4. Patients are on hemodialysis for 1-3 years. 5. Body mass index (BMI) range from 25-34.9 Kg/m2. 6. They will be medically and psychologically stable. 7. Receiving their physician-prescribed pharmacotherapy regularly. 8. Agree to participate by signing an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Inability to comprehend and follow instructions as in dementia or speech problems such as dysphasia. 2. Patients with unstable angina, uncontrolled cardiac arrhythmia, decompensated heart failure, persistent systolic blood pressure (BP) greater than 200 mmHg, persistent diastolic BP greater than 120 mmHg, acute pericarditis or myocarditis. 3. Acute systemic infection. 4. Presence of malignant disease. 5. Patients with Diabetes Mellitus. 6. Patients with Lupus Nephritis. 7. Patients with chronic obstructive lung disease, restrictive lung disease or chronic chest infection. 8. Severe obesity (BMI > 35). 9. Chronic inflammatory orthopedic disorders and rheumatoid arthritis. 10. Patients with muscle injuries or neuromuscular disorders (muscular dystrophy, myasthenia gravis, myopathy, multiple sclerosis and peripheral neuropathy).

Design outcomes

Primary

Measure	Time frame
- Muscle quality index: to measure muscle quality and function MQI (Watts) = ((Leg length×0.4) ×Bodymass×gravity×10) / Time taken for (sit to stand 5 times) - Six minute walk test (6MWT) to assess physical functional capacity - QOL by using the questionnaire “Medical Outcomes Study 36 (SF36)	—

Secondary

Measure	Time frame
kidney function urea, creatinine, BUN , creatine phosphokinase total and CPK-MB	—

Countries

Egypt

Contacts

Public Contacthala mohamed ezz eldeen

professor of physical therapy cairo university

hala.ezzeldeen@pt.cu.edu.eg01006626043

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026