Skip to content

Effect Meperidine on Agitation and Pain following Sevoflurane Anesthesia in Children

Effects of Single Intraoperative Dose of Meperidine on Agitation and Pain following Sevoflurane Anesthesia in Children undergoing Hypospadias Surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202302563630917
Enrollment
50
Registered
2023-02-08
Start date
2022-08-22
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery Anaesthesia

Interventions

Meperidine group

Sponsors

Mansoura University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 2-12 years old of either sex, ASA physical status I or II, scheduled for elective hypospadias surgery

Exclusion criteria

Exclusion criteria: any known history of allergy to study drugs, active or severe renal, hepatic, neuromuscular, neurological, pulmonary or cardiac disorder, congenital heart or endocrine disease, consumers of anticonvulsive drugs, sedatives or antihistamines, emergency surgery, confirmed moderate to severe obstructive sleep apnea (OSA) disorder, major life changes one month before the operation, such as divorce of parents, death of parents, moving to a new home, changing to a new kindergarten.

Design outcomes

Primary

MeasureTime frame
incidence of postoperative agitation in pediatrics using Pediatric Anesthesia Emergence Delirium (PAED) scores

Secondary

MeasureTime frame
Pain Scores using FLACC pain rating scale (Face, Leg, Activity, Cry, Consolability) intraoperative hemodynamics, the duration of anesthesia, total duration of PACU stay, time to first postoperative rescue analgesic received, incidence of PONV, respiratory depression or any side effect, extubation time

Countries

Egypt

Contacts

Public ContactHosam Saber

Assistant Professorof Anesthesia and Surgical ICU. Faculty of Medicine. Mansoura University

hosamsaber@yahoo.com+201005785775

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026