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Heat-stable carbetocin and tranexamic acid for postpartum hemorrhage prevention and treatment in basic emergency obstetric care facilities in fragile and humanitarian settings in South Sudan and Uganda

Heat-stable carbetocin and tranexamic acid for postpartum hemorrhage prevention and treatment in basic emergency obstetric care facilities: protocol for a complex mixed-method study in fragile and humanitarian settings in South Sudan and Uganda

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202302476608339
Enrollment
1008
Registered
2023-02-10
Start date
2022-01-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy and Childbirth

Interventions

Routine PPH prevention and treatment care
Package of intervention without HSC or TXA
Package of intervention with HSC but without TXA
Package of intervention with HSC and TXA

Sponsors

UNFPA Humanitarian Division
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: A woman will be eligible to participate in the study after she has (1) given birth at the facility and (2) provided informed consent (which will be done during the postpartum period before her discharge from the facility). Adult participants will give their informed consent. Non-adult participants will give their informed assent and their respective parents or guardians their informed consent.

Exclusion criteria

Exclusion criteria: (1) has not given birth at the facility (2) has not provided informed consent

Design outcomes

Primary

MeasureTime frame
1) proportion of birthing women receiving a uterotonic for PPH prevention. This overall proportion will be broken down by type of uterotonics that are available (e.g., oxytocin, misoprostol) or will be made available (HSC) in facilities; ;(2) proportion of women with clinical PPH receiving a uterotonic for PPH treatment (e.g., oxytocin, misoprostol);

Secondary

MeasureTime frame
(3) proportion of women with clinical PPH receiving TXA for PPH treatment.

Countries

Sudan, Uganda

Contacts

Public ContactCatrin;Raphael Okpwoku Schulte Hillen;sukere

Technical Advisor;UNFPA study coordinator

schulte-hillen@unfpa.org;sukere@unfpa.org+33631367376;+211929257248

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026