HIV/AIDS
Conditions
Interventions
Digital Adherence Device
Standard Care
Sponsors
KILIMANJARO CLINICAL RESEARCH INSTITUTE KCRI
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Mother/child/adolescent being HIV-positive 2. The infant of the mother being HIV exposed and aged less than 2 weeks 3. Attending Care and Treatment Centres (CTC) or postnatal clinics in Kilimanjaro and Arusha 4. Age of mother between 15-49 years, age of children living with HIV 0-14 years and adolescents living with HIV 15-19 years 5. Mother, caregiver/parents, and adolescents willing to use RTMM and/or receive SMS (participant will be provided with a phone if needed) 6. Mother, caregiver/parent, and adolescents able to read and understand SMS 7. Mother, caregiver/parent, and adolescents aged 18-19 able to understand and willing to sign informed consent 8. Adolescents aged 15-17 able and willing to sign informed assent.
Exclusion criteria
Exclusion criteria: 1. Admission to hospital at study-entry 2. Participation in other trials related to adherence and retention into care 3. Previous participation in digital health research 4. Participation in the formative stage
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Proportion of breastfeeding women retained in care at 18 months. 2. Proportion of children and adolescents with adherence of 95% over 12 months of follow up. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Breastfeeding women a) Percentage of infants found to be HIV positive in 24 months post-partum between those whose mothers use DAT and those in standard care b) Percentage of participants found to be virologically suppressed at month 12 and 24 between those who use DAT and those in standard care 2. Children and adolescents a) Percentage of participants found to be virologically suppressed at month 12 between those who use DAT and those in standard care 3. All groups a) Quality of life between those use DAT and those in standard care b) To investigate whether standardized questionnaires for stigmatization, depression, social support and quality of life are context-specific c) Feasibility and acceptability of the digital adherence tool d) Cost effectiveness of the digital adherence tool compare to the standard of care | — |
Countries
United Republic of Tanzania
Contacts
Public ContactKennedy Ngowi
Researcher at KCRI
Outcome results
None listed